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### Running command:
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###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:hipathia.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings hipathia_3.6.0.tar.gz
###
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* using log directory ‘/Users/biocbuild/bbs-3.20-bioc/meat/hipathia.Rcheck’
* using R version 4.4.3 (2025-02-28)
* using platform: aarch64-apple-darwin20
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 12.2.0
* running under: macOS Ventura 13.7.1
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘hipathia/DESCRIPTION’ ... OK
* this is package ‘hipathia’ version ‘3.6.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘hipathia’ can be installed ... OK
* checking installed package size ... NOTE
  installed size is  8.9Mb
  sub-directories of 1Mb or more:
    data      4.1Mb
    extdata   4.4Mb
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
DAreport: no visible binding for global variable ‘ID’
DAreport: no visible binding for global variable ‘FDRp.value’
DAtop : <anonymous>: no visible binding for global variable
  ‘FDRp.value’
DAtop : <anonymous>: no visible binding for global variable ‘statistic’
DAtop : <anonymous>: no visible binding for global variable ‘p.value’
DAtop : <anonymous>: no visible binding for global variable ‘name’
DAtop : <anonymous>: no visible binding for global variable ‘logPV’
DAtop : <anonymous>: no visible binding for global variable ‘feature’
DAtop: no visible binding for global variable ‘name’
DAtop: no visible binding for global variable ‘logPV’
DAtop: no visible binding for global variable ‘direction’
get_edges_df: no visible binding for global variable ‘from’
get_edges_df: no visible binding for global variable ‘to’
nsig_plot: no visible binding for global variable ‘total’
nsig_plot: no visible binding for global variable ‘UPs’
nsig_plot: no visible binding for global variable ‘DOWNs’
nsig_plot: no visible binding for global variable ‘feature’
nsig_plot: no visible binding for global variable ‘UP’
nsig_plot: no visible binding for global variable ‘DOWN’
nsig_plot: no visible binding for global variable ‘Not’
nsig_plot: no visible binding for global variable ‘value’
nsig_plot: no visible binding for global variable ‘variable’
prepare_DAedges: no visible binding for global variable ‘to’
prepare_DAedges: no visible binding for global variable ‘functional’
prepare_DAedges: no visible binding for global variable ‘status’
prepare_DAedges: no visible binding for global variable ‘type’
prepare_DAnodes : <anonymous>: no visible binding for global variable
  ‘ID’
prepare_DAnodes : <anonymous>: no visible binding for global variable
  ‘FDRp.value’
prepare_DAnodes : <anonymous>: no visible binding for global variable
  ‘statistic’
prepare_DAnodes : <anonymous>: no visible binding for global variable
  ‘p.value’
prepare_edges: no visible binding for global variable ‘to’
prepare_edges: no visible binding for global variable ‘functional’
summary_plot: no visible binding for global variable ‘total’
summary_plot: no visible binding for global variable ‘UPs’
summary_plot: no visible binding for global variable ‘DOWNs’
summary_plot: no visible binding for global variable ‘name’
summary_plot: no visible binding for global variable ‘UP’
summary_plot: no visible binding for global variable ‘DOWN’
summary_plot: no visible binding for global variable ‘Not’
summary_plot: no visible binding for global variable ‘value’
summary_plot: no visible binding for global variable ‘variable’
summary_plot: no visible binding for global variable ‘UP.nodes’
summary_plot: no visible binding for global variable ‘DOWN.nodes’
summary_plot: no visible binding for global variable ‘nodes’
summary_plot: no visible binding for global variable ‘ratio.sigs’
summary_plot: no visible binding for global variable ‘ratio.UPs’
summary_plot: no visible binding for global variable ‘ratio.DOWNs’
Undefined global functions or variables:
  DOWN DOWN.nodes DOWNs FDRp.value ID Not UP UP.nodes UPs direction
  feature from functional logPV name nodes p.value ratio.DOWNs
  ratio.UPs ratio.sigs statistic status to total type value variable
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... OK
* checking LazyData ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking sizes of PDF files under ‘inst/doc’ ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                           user system elapsed
quantify_terms           36.731  1.537  41.808
create_report            29.871  0.644  32.388
get_pathways_annotations 29.092  0.932  32.946
hipathia                 27.391  0.566  29.194
get_pathways_list        26.230  0.531  27.577
node_color_per_de        25.814  0.497  27.594
load_pathways            25.623  0.513  27.372
node_color               25.577  0.546  27.196
visualize_report         25.481  0.465  27.004
get_path_names           25.314  0.571  26.789
save_results             25.007  0.507  26.307
normalize_paths          24.919  0.461  26.395
get_pathways_summary     24.700  0.516  26.476
get_node_names           23.819  0.523  25.467
pathway_comparison_plot  22.562  0.488  24.274
normalize_data           21.719  0.521  23.186
translate_data           19.919  0.528  21.652
get_go_names              5.795  0.474   7.342
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 2 NOTEs
See
  ‘/Users/biocbuild/bbs-3.20-bioc/meat/hipathia.Rcheck/00check.log’
for details.

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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL hipathia
###
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* installing to library ‘/Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/library’
* installing *source* package ‘hipathia’ ...
** using staged installation
** R
** data
*** moving datasets to lazyload DB
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (hipathia)

R version 4.4.3 (2025-02-28) -- "Trophy Case"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: aarch64-apple-darwin20

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(testthat)
> library(hipathia)
Loading required package: igraph

Attaching package: 'igraph'

The following object is masked from 'package:testthat':

    compare

The following objects are masked from 'package:stats':

    decompose, spectrum

The following object is masked from 'package:base':

    union

Loading required package: AnnotationHub
Loading required package: BiocGenerics

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:igraph':

    normalize, path, union

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, aperm, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, saveRDS, setdiff, table,
    tapply, union, unique, unsplit, which.max, which.min

Loading required package: BiocFileCache
Loading required package: dbplyr
Loading required package: MultiAssayExperiment
Loading required package: SummarizedExperiment
Loading required package: MatrixGenerics
Loading required package: matrixStats

Attaching package: 'MatrixGenerics'

The following objects are masked from 'package:matrixStats':

    colAlls, colAnyNAs, colAnys, colAvgsPerRowSet, colCollapse,
    colCounts, colCummaxs, colCummins, colCumprods, colCumsums,
    colDiffs, colIQRDiffs, colIQRs, colLogSumExps, colMadDiffs,
    colMads, colMaxs, colMeans2, colMedians, colMins, colOrderStats,
    colProds, colQuantiles, colRanges, colRanks, colSdDiffs, colSds,
    colSums2, colTabulates, colVarDiffs, colVars, colWeightedMads,
    colWeightedMeans, colWeightedMedians, colWeightedSds,
    colWeightedVars, rowAlls, rowAnyNAs, rowAnys, rowAvgsPerColSet,
    rowCollapse, rowCounts, rowCummaxs, rowCummins, rowCumprods,
    rowCumsums, rowDiffs, rowIQRDiffs, rowIQRs, rowLogSumExps,
    rowMadDiffs, rowMads, rowMaxs, rowMeans2, rowMedians, rowMins,
    rowOrderStats, rowProds, rowQuantiles, rowRanges, rowRanks,
    rowSdDiffs, rowSds, rowSums2, rowTabulates, rowVarDiffs, rowVars,
    rowWeightedMads, rowWeightedMeans, rowWeightedMedians,
    rowWeightedSds, rowWeightedVars

Loading required package: GenomicRanges
Loading required package: stats4
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following object is masked from 'package:utils':

    findMatches

The following objects are masked from 'package:base':

    I, expand.grid, unname

Loading required package: IRanges
Loading required package: GenomeInfoDb
Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.


Attaching package: 'Biobase'

The following object is masked from 'package:MatrixGenerics':

    rowMedians

The following objects are masked from 'package:matrixStats':

    anyMissing, rowMedians

The following object is masked from 'package:AnnotationHub':

    cache

> 
> test_check("hipathia")
Computing pathway...
hsa03320 - PPAR signaling pathway 
hsa04012 - ErbB signaling pathway 
Computing pathway...
hsa03320 - PPAR signaling pathway 
hsa04012 - ErbB signaling pathway 
translated ids = 3184 (1) 
untranslated ids = 3 (0.00094) 
multihit ids = 0 (0) 
[ FAIL 0 | WARN 1 | SKIP 0 | PASS 119 ]

[ FAIL 0 | WARN 1 | SKIP 0 | PASS 119 ]
> 
> proc.time()
   user  system elapsed 
325.668   8.322 352.141