Package: GeoDiff
Type: Package
Title: Count model based differential expression and normalization on
        GeoMx RNA data
Version: 1.16.0
Authors@R: c(person("Nicole", "Ortogero", email = "nortogero@nanostring.com", role = c("cre")),
             person("Lei", "Yang", email = "lyang@nanostring.com", role = c("aut")), 
             person("Zhi", "Yang", email = "zyang@nanostring.com", role = c("aut")))
Description: A series of statistical models using count generating
        distributions for background modelling, feature and sample QC,
        normalization and differential expression analysis on GeoMx RNA
        data. The application of these methods are demonstrated by
        example data analysis vignette.
Imports: Matrix, robust, plyr, lme4, Rcpp (>= 1.0.4.6), withr, methods,
        graphics, stats, testthat, GeomxTools, NanoStringNCTools
LinkingTo: Rcpp, RcppArmadillo, roptim
License: MIT + file LICENSE
URL: https://github.com/Nanostring-Biostats/GeoDiff
BugReports: https://github.com/Nanostring-Biostats/GeoDiff
Encoding: UTF-8
Suggests: knitr, rmarkdown, dplyr
VignetteBuilder: knitr
Depends: R (>= 4.1.0), Biobase
RoxygenNote: 7.1.2
biocViews: GeneExpression, DifferentialExpression, Normalization
Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev
        libfreetype6-dev make libicu-dev libpng-dev libssl-dev
        zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 15:13:32 UTC
RemoteUrl: https://github.com/bioc/GeoDiff
RemoteRef: RELEASE_3_22
RemoteSha: 0185ce6be6360966cc682c6c673ef80015264b06
NeedsCompilation: yes
Packaged: 2026-01-24 20:29:56 UTC; root
Author: Nicole Ortogero [cre],
  Lei Yang [aut],
  Zhi Yang [aut]
Maintainer: Nicole Ortogero <nortogero@nanostring.com>
Built: R 4.5.2; x86_64-w64-mingw32; 2026-01-24 20:32:15 UTC; windows
Archs: x64
