\documentclass[a4paper,12pt,nogin]{article} %\VignetteIndexEntry{Manual for the chroGPS library} %\VignettePackage{chroGPS} \usepackage{amsmath} % need for subequations \usepackage{amssymb} %useful mathematical symbols \usepackage{bm} %needed for bold greek letters and math symbols \usepackage{graphicx} % need for PS figures %\usepackage{verbatim} % useful for program listings %\usepackage{color} % use if color is used in text \usepackage{hyperref} % use for hypertext links, including those to external documents and URLs \usepackage{natbib} %number and author-year style referencing %\usepackage{epsf} %\usepackage{lscape} %\bibpunct{(}{)}{;}{a}{,}{,} \usepackage[hmargin=2.5cm,vmargin=3cm]{geometry} %\pagestyle{empty} % use if page numbers not wanted \begin{document} \title{\texttt{chroGPS}: navigating through the epigenome. } \small \author{Oscar Reina \footnote{Bioinformatics \& Biostatistics Unit, IRB Barcelona} and David Rossell \footnotemark[1] } \normalsize \date{} %comment to include current date \maketitle \section{Introduction} \label{sec:intro} The \texttt{chroGPS} package provides tools go generate intuitive maps to visualize the association between genetic elements, with emphasis on epigenetics. The approach is based on Multi-Dimensional Scaling. We provide several sensible distance metrics, and adjustment procedures to remove systematic biases typically observed when merging data obtained under different technologies or genetic backgrounds. Many routines are designed to perform computations in parallel by specifying an argument \texttt{mc.cores}, which uses package \texttt{multicore}. As this package is not available in all platforms, currently only Unix/Linux and Mac OS X versions of the package are supported. Please see the help page for each function for more details. You will find the full vignette for the chroGPS package with detailed examples in the chroGPS-manual.pdf file included in the inst/doc folder. \end{document}