# On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs

## Documentation for package ‘crisprScore’ version 1.15.0

- DESCRIPTION file.
- User guides, package vignettes and other documentation.
- Package NEWS.

## Help Pages

getAzimuthScores | Calculate on-target sgRNA activity scores for Cas9 using Azimuth
getCasRxRFScores | Calculate on-target sgRNA activity scores for CasRx using CasRx-RF
getCFDScores | Calculate CFD off-target specificity scores
getCrispraiScores | Calculate on-target sgRNA activity scores for CRISPRa and CRISPRi
getCRISPRaterScores | Calculate on-target sgRNA activity scores for Cas9 using CRISPRater
getCRISPRscanScores | Calculate on-target sgRNA activity scores for Cas9 using CRISPRscan
getDeepCpf1Scores | Calculate on-target sgRNA activity scores for Cas12a using DeepCpf1
getDeepHFScores | Calculate on-target sgRNA activity scores for Cas9 using DeepHF
getDeepSpCas9Scores | Calculate on-target sgRNA activity scores for SpCas9 using DeepSpCas9
getEnPAMGBScores | Calculate on-target sgRNA activity scores for enCas12a using enPAM+GB
getLindelScores | Predict frameshift ratios from CRISPR/Cas9 indel prediction using Lindel
getMITScores | Calculate MIT off-target specificity scores for CRISPR/Cas9
getRuleSet1Scores | Calculate on-target sgRNA activity scores for Cas9 using Rule Set 1
getRuleSet3Scores | Calculate on-target sgRNA activity scores for SpCas9 using Rule Set 3
scoringMethodsInfo | data.frame detailing available scoring methods
sgrnaExampleCrispra | Example CRISPRa gRNAs data.frame for the getCrispraiScores function
sgrnaExampleCrispri | Example CRISPRi gRNAs data.frame for the getCrispraiScores function
tssExampleCrispra | Example TSS data.frame for the getCrispraiScores function
tssExampleCrispri | Example TSS data.frame for the getCrispraiScores function